How circulating innate immune cells
sense and respond to mechanical forces
Amitabha Mukhopadhyay
I’m a researcher based out of University of Illinois Chicago. My research focus is to understand the mechanism of mechanical signal relay in neutrophils and innate immune cells.
Publication
1. trans-Endothelial neutrophil migration activates bactericidal function via Piezo1 mechanosensing.
Immunity. 2023 Dec 12;. doi: 10.1016/j.immuni.2023.11.007. [Epub ahead of print] PubMed PMID: 38091995.
Mukhopadhyay A, Tsukasaki Y, Chan WC, Le JP, Kwok ML, Zhou J, Natarajan V, Mostafazadeh N, Maienschein-Cline M, Papautsky I, Tiruppathi C, Peng Z, Rehman J, Ganesh B, Komarova Y, Malik AB.
J Exp Med. 2023 Nov 6;220(11). doi: 10.1084/jem.20221388. Epub 2023 Aug 24. PubMed PMID: 37615937; PubMed Central PMCID: PMC10450795.
Chakraborty S, Singh A, Wang L, Wang X, Sanborn MA, Ye Z, Maienschein-Cline M, Mukhopadhyay A, Ganesh BB, Malik AB, Rehman J.
Nat Commun. 2023 Oct 18;14(1):6582. doi: 10.1038/s41467-023-42225-2. PubMed PMID: 37852964; PubMed Central PMCID: PMC10584835.
Tiruppathi C, Wang DM, Ansari MO, Bano S, Tsukasaki Y, Mukhopadhyay A, Joshi JC, Loch C, Niessen HWM, Malik AB.
4. Nanoparticle targeting of de novo profibrotic macrophages mitigates lung fibrosis.
Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2121098119. doi: 10.1073/pnas.2121098119. Epub 2022 Apr 4. PubMed PMID: 35377803; PubMed Central PMCID: PMC9169714.
Singh A, Chakraborty S, Wong SW, Hefner NA, Stuart A, Qadir AS, Mukhopadhyay A, Bachmaier K, Shin JW, Rehman J, Malik AB.
ACS Nano. 2022 Mar 22;16(3):4084-4101. doi: 10.1021/acsnano.1c09762. Epub 2022 Mar 1. PubMed PMID: 35230826; PubMed Central PMCID: PMC8945372.
Bachmaier K, Stuart A, Singh A, Mukhopadhyay A, Chakraborty S, Hong Z, Wang L, Tsukasaki Y, Maienschein-Cline M, Ganesh BB, Kanteti P, Rehman J, Malik AB.
Am J Respir Cell Mol Biol. 2022 Feb;66(2):183-195. doi: 10.1165/rcmb.2021-0272OC. PubMed PMID: 34706199; PubMed Central PMCID: PMC8845142.
Farahany J, Tsukasaki Y, Mukhopadhyay A, Mittal M, Nepal S, Tiruppathi C, Malik AB.
7. Selective Nanotherapeutic Targeting of the Neutrophil Subset Mediating Inflammatory Injury.
bioRxiv. 2020 June; 180927. doi: https://doi.org/10.1101/2020.06.30.180927.
Bachmaier K, Stuart A, Hong Z, Tsukasaki Y, Singh A, Chakraborty S, Mukhopadhyay A, Gao X, Maienschein-Cline M, Kanteti P, Rehman J, Malik A.
8. Recording Ion Channels in Cilia Membranes. In: Polycystic Kidney Disease
Book Chapter (Polycystic Kidney Disease); First Published 2019. CRC Press, Routledge Taylor & Francis; 1st Edition; Pages18, eBook ISBN 9780429468834
Ng LC, Mukhopadhyay A, Vien N, DeCaen PG.
9. 14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression.
Sci Rep. 2016 Jun 2;6:26580. doi: 10.1038/srep26580. PubMed PMID: 27253419; PubMed Central PMCID: PMC4890593.
Mukhopadhyay A, Sehgal L, Bose A, Gulvady A, Senapati P, Thorat R, Basu S, Bhatt K, Hosing AS, Balyan R, Borde L, Kundu TK, Dalal SN.
J Cell Sci. 2014 May 15;127(Pt 10):2174-88. doi: 10.1242/jcs.125807. Epub 2014 Mar 7. PubMed PMID: 24610948.
Sehgal L, Mukhopadhyay A, Rajan A, Khapare N, Sawant M, Vishal SS, Bhatt K, Ambatipudi S, Antao N, Alam H, Gurjar M, Basu S, Mathur R, Borde L, Hosing AS, Vaidya MM, Thorat R, Samaniego F, Kolthur-Seetharam U, Dalal SN.
Indian J Exp Biol. 2012 Oct;50(10):669-76. PubMed PMID: 23214259.
Sehgal L, Budnar S, Bhatt K, Sansare S, Mukhopadhaya A, Kalraiya RD, Dalal SN.
12. Lentiviral mediated transgenesis by in vivo manipulation of spermatogonial stem cells.
PLoS One. 2011;6(7):e21975. doi: 10.1371/journal.pone.0021975. Epub 2011 Jul 7. PubMed PMID: 21760937; PubMed Central PMCID: PMC3131306.
Sehgal L, Thorat R, Khapare N, Mukhopadhaya A, Sawant M, Dalal SN.
Current Location